Women Diary Network >> Women Pregnancy

Polycystic Ovary Syndrome and Insulin Resistance

PCOS (Polycystic Ovarian Syndrome) is a health problem that can affect a woman’s menstrual cycle, fertility, hormones, insulin production, heart, blood vessels, and appearance. It’s hormonal imbalance linked to the way the body processes insulin after it has been produced by the pancreas to regulate blood sugar (glucose). Features of PCOS may manifest at any age, ranging from childhood (premature puberty), teenage years (hirsutism, menstrual abnormalities), early adulthood and middle life (infertility, glucose intolerance) to later life (diabetes mellitus and cardiovascular disease).

Insulin resistance seems to be a key feature in polycystic ovarian syndrome. The underlying cause of PCOS, Insulin Resistance, has many factors that contribute to its presence in the body. The increased incidence of insulin resistance occurs in all PCOS women, not simply obese women. When someone is insulin resistant, this means that cells throughout the body do not readily respond to the insulin circulating in the blood.
Most women with polycystic ovary syndrome (PCOS) are obese and are known to be insulin resistant. Obesity per se is a cause of insulin Syndrome X. The hormone insulin is primarily known for its role in glucose regulation. Under normal circumstances, insulin assures the efficient transfer of glucose from the bloodstream to the body. Insulin also serves as a signal to the liver to begin or discontinue glucose production.

One of the most important issues is determining whether you have PCOS. There are other endocrine disorders that are similar to PCOS, and it is important that you work with your doctor to determine if you have PCOS, or something else.
Polycystic ovary syndrome
- Presence of menstrual abnormalities and anovulation
- Presence of clinical and/or biochemical hyperandrogenaemia
- Absence of hyperprolactinaemia or thyroid disease
- Absence of late-onset congenital adrenal hyperplasia
- Absence of Cushing’s syndrome

At present, there are no pharmaceutical drugs that can heal PCOS. Even the removal of the ovaries will not completely eliminate this disorder. A complete system of elements is needed to treat this condition’s underlying cause, Insulin Resistance.
A significant degree of insulin resistance exists in non-obese women with PCOS and is significantly related to serum LH and free testosterone levels.
Therefore, measures to decrease this condition may have to be considered earlier to decrease the potential risks of developing diabetes mellitus and coronary artery disease at later ages of life in both overweight and normal weight women who have PCOS.

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